We are independent & ad-supported. We may earn a commission for purchases made through our links.

Advertiser Disclosure

Our website is an independent, advertising-supported platform. We provide our content free of charge to our readers, and to keep it that way, we rely on revenue generated through advertisements and affiliate partnerships. This means that when you click on certain links on our site and make a purchase, we may earn a commission. Learn more.

How We Make Money

We sustain our operations through affiliate commissions and advertising. If you click on an affiliate link and make a purchase, we may receive a commission from the merchant at no additional cost to you. We also display advertisements on our website, which help generate revenue to support our work and keep our content free for readers. Our editorial team operates independently from our advertising and affiliate partnerships to ensure that our content remains unbiased and focused on providing you with the best information and recommendations based on thorough research and honest evaluations. To remain transparent, we’ve provided a list of our current affiliate partners here.

How do I Use Tretinoin for Acne?

Anna T.
By
Updated May 17, 2024
Our promise to you
WiseGEEK is dedicated to creating trustworthy, high-quality content that always prioritizes transparency, integrity, and inclusivity above all else. Our ensure that our content creation and review process includes rigorous fact-checking, evidence-based, and continual updates to ensure accuracy and reliability.

Our Promise to you

Founded in 2002, our company has been a trusted resource for readers seeking informative and engaging content. Our dedication to quality remains unwavering—and will never change. We follow a strict editorial policy, ensuring that our content is authored by highly qualified professionals and edited by subject matter experts. This guarantees that everything we publish is objective, accurate, and trustworthy.

Over the years, we've refined our approach to cover a wide range of topics, providing readers with reliable and practical advice to enhance their knowledge and skills. That's why millions of readers turn to us each year. Join us in celebrating the joy of learning, guided by standards you can trust.

Editorial Standards

At WiseGEEK, we are committed to creating content that you can trust. Our editorial process is designed to ensure that every piece of content we publish is accurate, reliable, and informative.

Our team of experienced writers and editors follows a strict set of guidelines to ensure the highest quality content. We conduct thorough research, fact-check all information, and rely on credible sources to back up our claims. Our content is reviewed by subject matter experts to ensure accuracy and clarity.

We believe in transparency and maintain editorial independence from our advertisers. Our team does not receive direct compensation from advertisers, allowing us to create unbiased content that prioritizes your interests.

To use tretinoin for acne, you should probably wait until just before you go to bed at night to apply it. Wash your face thoroughly with warm water and mild soap and then dry your face completely. Put just a pea-sized amount of tretinoin on your fingertip and rub it evenly into your skin, concentrating only on the areas where acne is a problem. When you wake up the next morning, you can wash your face again with warm water and a mild soap. It might also be a good idea to use a moisturizer with built-in sunscreen on your skin during the day after using tretinoin for acne at night.

Your dermatologist may have different instructions for you regarding the use of tretinoin for acne, but in most cases it should not be applied more than once per day. During the first few weeks of using tretinoin, you might notice that your skin becomes very dry, red, and flaky. Many people stop using tretinoin when they notice the redness and flaking, but these side effects typically become less severe after the first few months. Being diligent about using moisturizer on your skin while you use tretinoin for acne can greatly help relieve the flaking and discomfort you might experience.

You should be careful not to use any other acne medication on your skin while you use tretinoin. Other acne medicines combined with tretinoin could produce some unpleasant side effects. Even over-the-counter acne medicines should typically be avoided until you are finished with your tretinoin treatment. You will likely be much more sensitive to sunlight when using tretinoin and may sunburn more easily than before, so you should take care to either use a sunscreen or apply makeup or moisturizer that has a sunscreen built in. Pregnant women are typically advised to avoid tretinoin for acne because it could be dangerous for fetuses, so if there is a chance you could be or might become pregnant, you should consult with your dermatologist about other methods of acne treatment.

It could take you a few months of using tretinoin for acne before you begin to notice an improvement in your skin. For some people, results are not visible for up to nine weeks. Even though side effects, such as skin irritation, burning, and redness, are common with tretinoin use, you should still report all side effects you experience to your dermatologist. If your side effects are incredibly severe, your dermatologist may decide that you should discontinue tretinoin for acne.

WiseGEEK is dedicated to providing accurate and trustworthy information. We carefully select reputable sources and employ a rigorous fact-checking process to maintain the highest standards. To learn more about our commitment to accuracy, read our editorial process.
Anna T.
By Anna T.
Anna Thurman is a skilled writer who lends her talents to WiseGEEK. Her ability to research and present information in an engaging and accessible manner allows her to create content that resonates with readers across a wide range of subjects.

Discussion Comments

By ysmina — On May 24, 2013

@turquoise-- That's true. More than a pea-sized is not needed anyway because this stuff really dries out the skin. I always have to moisturize with an oil-free face lotion with sun protection after I use tretinoin cream for acne. Otherwise, my skin becomes very flaky and itchy, I also get sun-burnt.

By turquoise — On May 23, 2013
@anamur-- Yes, they're used the same way. Apply a pea-sized amount on your skin at least twice a day.

I want to emphasize the pea-sized amount, especially when you're using tretinoin cream because more than that can actually trigger a breakout.

I made that mistake when I first started using tretinoin treatment for acne. I was using the cream which has some ingredients that can potentially clog pores. It's not a problem when only a pea-sized is used. But if you lather it on like I did, it can clog pores and cause more breakouts at first. So follow the directions carefully.

By serenesurface — On May 22, 2013

Are tretinoin cream and tretinoin gel used the same way?

Anna T.

Anna T.

Anna Thurman is a skilled writer who lends her talents to WiseGEEK. Her ability to research and present information in an engaging and accessible manner allows her to create content that resonates with readers across a wide range of subjects.
WiseGEEK, in your inbox

Our latest articles, guides, and more, delivered daily.

WiseGEEK, in your inbox

Our latest articles, guides, and more, delivered daily.