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What are the Most Common Curcumin Side Effects?

By Aniza Pourtauborde
Updated May 17, 2024
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Curcumin is an active ingredient in turmeric, an herb that is most often used as curry spice and yellow food coloring. It also carries medicinal properties and is part of many traditional Ayurvedic and Chinese treatments for health problems such as indigestion, jaundice, dysentery, arthritis, and chest congestion. A natural product, many people do not suffer any side effects when consuming it for health purposes. Even clinical studies show that it is safe to be taken in small doses daily. There are, nevertheless, some common side effects to be aware of.

One of these is contact dermatitis that develops on the skin or scalp of those who are allergic to curcumin. This condition normally begins with the presence of a red rash on the exposed area, which appears within 24 to 72 hours of exposure. Without treatment, the skin continues to itch and burn, after which blisters, welts, or hives may develop.

Mild stomach distress is another side effect when curcumin is take in high doses and for a prolonged period of time. Since it may be used to treat heartburn and stomach ulcers, use of higher than the recommended dosage can upset the stomach and eventually bring about severe nausea and diarrhea.

Curcumin is known to stimulate the uterus and may also cause menstrual flow. These two curcumin side effects present a particular risk to women who are pregnant, as taking it during a pregnancy raises the risk of a miscarriage. Women are thus discouraged from consuming this herb at all throughout their pregnancy.

Curcumin side effects also include an increased risk of bleeding. Since curcumin slows down the clotting of blood, it is not recommended for those who have preexisting bleeding disorders. Furthermore, the risk of bleeding out is increased when it is taken together with other drugs, like anticoagulants. Curcumin can also cause more bleeding during and after surgery, and should not be consumed for at least two weeks before surgery.

One of the more severe side effects is that it can be poisonous to the liver and gallbladder when taken in very high doses and for an extended time. Curcumin eases the flow of bile from the liver, and in this way helps prevent the formation of gallstones. It is an ineffective treatment, however, if there are already gallstones in the gallbladder. In fact, curcumin may exacerbate the problem by flushing existing gallstones through the bile duct, and blocking it.

There are some serious curcumin side effects when it is taken by people with certain diseases, such as diabetes. Some research has shown that curcumin might lower blood sugar; since many diabetics are already taking medication to control their blood sugar, taking curcumin could contribute to complications. There is also some indication that it could lower blood pressure, so people on blood pressure medication may want to avoid it.

WiseGEEK is dedicated to providing accurate and trustworthy information. We carefully select reputable sources and employ a rigorous fact-checking process to maintain the highest standards. To learn more about our commitment to accuracy, read our editorial process.

Discussion Comments

By anon997491 — On Jan 16, 2017

I'm here because I too, as a new user of nanocurcumin, a fast absorbing version of the supplement (500mg twice a day as the guide says), I too have had a weird problem.

I've been taking it two days only and a couple of spots seem to have developed inside one of my nostrils. They are painful to touch and I have swelling on one side of my nose.

I will stop using them and see if it clears up. My lower back pain has markedly improved for the last two mornings I will also add. This is the reason I will more slowly reintroduce it and hope my body gets used to it.

By anon996720 — On Oct 07, 2016

Love taking my golden milk but I've been getting headaches. Will try to cut the dose down and try something different.

By anon993150 — On Oct 26, 2015

The day after I started taking a 95 percent curcumin supplement, I started getting a sore mouth. I continued taking it for a week and continued having the same problem - sore spots on my tongue (not ulcerated, just painful in places where my tongue hits sharp edges of my lower teeth) and sore, sensitive gums. I've also noticed a strange sensation inside my lips, as if they're about to peel.

All in all, it has been very unpleasant and has prompted me to discontinue the supplement. I stopped it two days ago and have noticed some improvement, so I'm inclined to think this was indeed the causative agent. Has anyone else experienced mouth side effects from this?

By anon991725 — On Jul 13, 2015

I too have had bad headaches since taking Curcumin and am at the point of stopping because it obviously is not as good as recommended.

By anon990990 — On May 20, 2015

Excellent article, I keep getting a red flushed face that can sometimes turn to spots after eating and drinking. It can be different things so am struggling to find the culprit but with this article and another I think I have pinpointed Curcumin and Annato so am going to try cutting these out and see if my face improves.

By anon958337 — On Jun 26, 2014

I almost never get headaches from a very healthy lifestyle. I started 500mg Doctor's Best curcumin. I had powerful headaches that only went away after stopping the supplement. It did help with my main ailment. With supplements they are processed with chemicals to provide standardised curcumin (vs plain powdered turmeric). I wonder if switching brands or consuming the unprocessed powder may make a difference. People forget that the supplement industry is very loosely regulated, so who knows how they are processed and what residues remain?

By anon954107 — On May 29, 2014

I'm on Xeralto, a blood thinner. I'm taking 500 mg. Circumin daily. Am I going to bleed to death?

By anon943993 — On Apr 05, 2014

It is ridiculous to tell diabetics and hypertensives to avoid curcumin when it could improve their condition! Better to advise close monitoring and reducing pharmaceuticals as needed.

By anon925398 — On Jan 11, 2014

I have taken curcumin for many months approximately 1200MG a day. Works amazing for arthritis, however I have edema swelling in the neck and abdomen which is new. When I stop it goes away in a week, restart comes back. Is this a side effect?

By anon360273 — On Dec 25, 2013

I agree with "anon301023" Start slow. I had a very similar experience. I've had a rash now for two months. I don't think mine is as bad as his, but the rash still continues five weeks after I've stopped.

I didn't start seeing the rash for about three weeks. First, I had low grade headache and felt flushed and hot, but I didn't have a fever.

Then the rash started. I went to the doctor and he asked if I'd started anything new and that reminded me of the turmeric supplement. I stopped immediately.

I've been to the doctor four times, had a skin biopsy and they have no clue.

I'm using a steroid cream which lessens the symptoms, and now they seem to be letting up a bit. Hopefully, this doesn't go on for another two months.

Cucumin is not a panacea. Be careful.

By anon353334 — On Oct 29, 2013

It can cause nosebleeds.

By anon301023 — On Nov 01, 2012

I have large, painful and horrible-looking skin blisters on both arms and both legs from taking 875 mg capsules of Curcumin twice daily for about three weeks.

This side effect has gone on for three months now, and new blisters continue to erupt. The blisters appeared within the first week of use and appear to be the result an allergy to Curcumin.

I thought they were infected mosquito bites at first, so I continued to take this supplement for an additional two weeks. After I did the research and read about the side effects, I discontinued the Curcumin, but I continue to have problems.

I have switched to hypo-allergenic shampoo and body soap, used a prescription ointment called Clobetasol Propionate 0.05 percent strength, taken two weeks of Amoxicillin antibiotic and nothing is helping!

So for now I will continue wear long pants and long-sleeved shirts to work to hide these horrible blisters and keep searching for my cure. If/when I find something that works, I will post it here.

I have learned a valuable lesson. No matter what other people say, I need to start with small doses (of anything) and closely monitor my body's reaction.

Had I discontinued this supplement earlier, I might not have experienced these side-effects as severely or for as long.

By anon185195 — On Jun 10, 2011

"There are some serious curcumin side effects when it is taken by people with certain diseases such as diabetes and high blood pressure." You are full of crap. Show me the studies.

By anon139328 — On Jan 04, 2011

This article is interesting but totally useless without a definition of "high" dosage. Please add that information.

By googlefanz — On Dec 18, 2010

Although turmeric (curcumin) does have side effects, there are also a lot of benefits to taking curcumin as well.

For instance, studies have shown that curcumin really benefits your circulatory system, and can help lower cholesterol. This is really great news for people who have been taking things like niacin to try and lower their cholesterol, since it doesn't give you that characteristic hot flash and flush thing.

Also, curcumin is supposed to be really good for improving your state of mind. It is supposed to bring mental clarity, help prevent depression, and can also relieve stress.

Finally, curcumin supplements have also been shown to improve the appearance of the skin and hair, which can be a godsend in the winter when they tend to get dull.

So although curcumin supplements do have side effects, they are definitely worth it to the thousands of people who take them every day.

By closerfan12 — On Dec 16, 2010

I have a question -- I started taking a low dosage of turmeric lately for my menstruation, and although I followed the exact curcumin dosage that it mentioned on the bottle, I still seem to be getting uncomfortable side effects.

I don't have the rash (thank God!) but my stomach just seems really upset all the time, and I've had a headache on and off for a few days. I also seem to be retaining slightly more water than usual, so I was wondering if that could have anything to do with it as well.

Could the headache and the water retention be side effects of curcumin as well, or are they unrelated? Also, should I stop taking this supplement, or keep taking it in hopes that my body will adjust to it?

Any information would be very appreciated!

By naturesgurl3 — On Dec 15, 2010

Excellent article! I work in a natural foods and medicines store, and you wouldn't believe the people who think that you can just take herbal supplements like crazy and not expect any bad side effects.

It's weird, it's like they think that just because its made from a plant it can't hurt you. In fact, a few weeks ago I had a lady who completely exceeded the curcumin dose printed on the bottle of curcumin supplements we sold her, and then tried to bring it back afterwards, saying that it was obviously not suitable for her "dosha" since it didn't work right the first time and made her stomach hurt.

Doshas aside, if you take a medicine like that improperly, it's not the problem of the medicine -- it's you! So listen to you doctors and naturopaths when they tell you about the side effects of medications. Just because it's herbal doesn't mean that it can't really mess you up if you don't take it properly.

Namaste!

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