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What is Ipratropium Bromide Nasal Spray?

By M. DePietro
Updated May 17, 2024
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Ipratropium bromide nasal spray is a medication used to treat symptoms of perennial rhinitis, such as a runny nose. Many asthma inhalers also contain ipratropium bromide, and it is often one of the drugs prescribed along with albuterol to treat asthma. When it is prescribed in the form of a nasal spray, it is intended to treat only rhinitis, not asthma.

The nasal spray is indicated for runny noses, which may be caused by allergies or a cold. It does not treat other symptoms of a cold, such as cough, nasal congestion, or sneezing. Ipratropium bromide an anticholinergic drug. When it is used as a nasal spray, it reduces the amount of mucus by reducing how much fluid is produced in the nasal passages. This drug is approved by the United States Food and Drug Administration (FDA) for adults and children over the age of six.

Ipratropium bromide nasal spray is available with a prescription from a medical professional and not available over the counter. Although the dosage may vary, most people are prescribed two sprays in each nostril up to three times a day while they have a runny nose. The dose for children may be less.

When first using the nasal spray, it must be pumped seven times to prime it for use. If the spray is not used for a week, it should be primed again with seven sprays. When priming the pump, users should point it away from the face to prevent the medication from going into the eyes or lungs.

Unlike asthma inhalers, the nasal spray is not meant to be inhaled deeply into the lungs — it is simply sprayed into the nostrils. It works when it comes in contact with the lining of the nasal passages. One nostril should be held closed while using the spray, and patients should sniff the spray in in without inhaling too deeply.

The most common side effects of this medication are dry nose, nosebleed, and headache. Some people may also experience blurred vision. It is also possible to develop nasal congestion and a sore throat when using the medication. Taste changes and nausea are unlikely, but can occur. Occasionally, some people may have an increase in heart rate, but this is also rare. When the medication is used longer or at higher doses than recommended, there is an increased likelihood of certain side effects, such as nasal irritation.

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Discussion Comments

By anon1003761 — On Sep 01, 2020

@Theo1934 The packaging/bottle for mine specifies "165 metered sprays" and counting the 5 prime sprays and 4 (2/2) per use, I have 40 uses per bottle. I draw a 8x5 grid on the box and write the date in so I don't miss a day, but any way to track how many sprays you've used should work.

By theo1934 — On Sep 22, 2019

I noticed that the spray works even when all the solution is gone.

How can you tell that the latter has happened, besides realizing that the medication is ineffective and start using a new bottle?

By anon989371 — On Mar 03, 2015

Since using this, I've had headaches, blurred vision and cold symptoms.

By candyquilt — On Apr 15, 2013

Is it possible to get addicted to ipratropium bromide nasal solution?

By ddljohn — On Apr 14, 2013

@fify-- I haven't experienced anxiety or heart palpitations on this nasal spray. It just makes me feel like I have a common cold. I feel tired and I get a runny nose.

It might be the other drug causing your symptoms. The worst things I've heard about ipratropium is that it can make breathing more difficult or cause a fever. Throat irritation is also common but that's very minor.

If you're having a lot of side effects, you should ask your doctor to switch you to a different nasal spray. There are a lot of options out there and ipratropium bromide also comes combined with several other drugs like fenoterol. You might do better on one of these.

By fify — On Apr 14, 2013

My doctor prescribed a nasal spray for my asthma symptoms. It's a combination of ipratropium bromide and albuteral. It works but I've been experiencing a lot of side effects from it. I feel nauseated and very anxious. Sometimes it also feels like my heart is beating very quickly.

I don't know if these symptoms are from the ipratropium or from the other drug. Has anyone else experienced these symptoms on ipratropium bromide nasal spray?

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